The most current scientific and theoretical, cognitive and practical problems are considered in the publication. These problems are the main content of the discipline. Particular attention is given to significant, meaningful psychologically and engineering basis for the activity of the Man-Machine system operators. The unity of theoretical positions is clearly defined with practical actions of operators as the specialists of system-technical devices. The unity of theoretical positions is also defined with practical actions of operators as the specialists that ensure the effective implementation of the tasks in extreme situations. The textbook is designed for students who study engineering psychology in accordance with the areas of professional training and for lecturers who prepare these professionals. The publication can be useful for practical psychologists.